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Dimethyl Isosorbide (Arlasolve DMI)

  - Active delivery Enhancement system

Efficient Delivery System


dmi molecular
Active ingredients are being used more and more in skin care formulations to give efficacious products for personal care applications. The more efficient the delivery system used, the more likely it will be the active ingredient will perform as required. Dimethyl Isosorbide (Arlasolve DMI) has undergone extensive toxicological studies for both topical and oral drug delivery and has Dimethyl Isosorbide (Arlasolve DMI) been shown to be virtually free of irritation and its completely safe for use.



Cosmetic products which have efficacy claims to deliver what they promise. With Dimethyl Isosorbide (Arlasolve DMI) the formulator has a number of options to enhance the delivery of active ingredients without having to add more active. Effective delivery of actives such as Vitamin C, Lactic Acid, Kojic Acid, Salicylic Acid, and Hyaluronic Acid can even lead to a reduction in the amount of active levels required to give the effect claimed.


Other Benefits from DMI

  • Enhanced penetration of actives to the upper layers of the epidermis.
  • A lower level of skin irritation in the formulation due to reduction in the required concentration level
  • Improved stability of formulations -even those susceptibility to hydrolysis and transesterification.
  • A long history of safe usage
  • Ability to deliver water soluble actives into the skin

    Active Delivery Enhancement


    Dimethyl Isosorbide (Arlasolve DMI) can be used to aid penetration of actives into the skin. Work has been carried by Uniquema using a hydrophilic active. The results below support the claim that Dimethyl Isosorbide (Arlasolve DMI) enhances delivery into the epidermis but does not promote the product into the bloodstream.


    In Vivito Testing

    The improvement in active delivery can be very well in self-tanning products. At 5%, DMI in a self-tanning cream exhibits markedly improved color development.
    dmi delivery