Thermus Thermophilus (Venuceane™)

molecules
sub venuceane bar

  -Protection of cell membrane lipids against UVA rays

Function

Thermus Thermophilus
Heat Activated strong anti-oxidant

 

Definition

Biotechnical product obtained the culture of Thermus Thermophilus

 

Properties

Inhibits radical oxygen species. Repairs and protects against damages caused by UVA.

 

Characteristics

Thermo-stable, UV-stable, inexhaustible enzyme activity. Increasing efficacy with rising temperature.

 

Origin

Thermus Thermophlius lives in deep sea, under extreme conditions (2000m depth, 75 degree C temperature, and 200 bars pressure)

 

In Vitro Tests

Thermus Thermophilus (Venuceane™) displays a similar activity to native skin enzyme scavengers of toxic oxygen species such as super oxide and ion O+-2 hydrogen peroxide H2O2.
Venuceane
catalase like activity
o2 scavenger activity
Thermus Thermophilus (Venuceane™) detoxifying activity increases with temperature.

 

In vivo Tests - Protection Agaist memrane lipid peroxidation

Protection Agaist memrane lipid peroxidation
UVA irradiation: 15J/cmm2(equivalent to 11/2 hour exposure on a sunny day.

 

In vivo Tests - Protection against membrane lipid peroxidation

Protection Agaist memrane lipid peroxidation
UVA irradiation: 60J/Cm2 Equivalent to 6 hours exposure on a sunny day.

 

In vivo Tests - Membrane protection of temperature

thermus thermophilus temperature
Model of phospholipid membranes exposed to a dose of 10 J/cm2 of UVA irradiation (equivalent to 1 hour exposure on a sunny day) Measurement of lipid peroxidation.

Thermus Thermopilus (Venuceane™) strongly protects phospholipids from peroxidation.

 

In vivo Tests - Protection of the skin's natural detoxifying enzymes

thermus thermophilus enzym
Protocol: Application of a gel on the arm for 1 hour

Thermus Thermophilus (Venuceane™) adapts and maintains skin's natural protection much higher than Vitamin E acetate.

 

In vivo Tests - Protection against DNA oxidation

thermus thermophilus uva
Fluorescence detection of oxidation DNA base Guanine of human fibroblasts with 3% with Vitamin E acetate 0.1% after exposure to 10 J/cm2 UVA (equivalent to 1 hour exposure on a sunny day) Thermus Thermophilus (Venuceane™) protects DNA from oxidation caused by UVA irradiation.

 

thermus thermophilus dna
Thermus Thermophilus (Venuceane™) protects DNA from oxidation caused by UVA irradiation.

 

In vivo Tests - Protection against lipoperoxidation

thermus thermophilus protection
Model of phospholipid membranes exposed to a dose of 10J/cm2 of UVA irradiation (equivalent to 1 hour exposure on a sunny day)
Thermus Thermophilus (Venuceane™) adapts and maintains skin's natural protection .